Education
- 2012 鈥� 2016: PhD in Pathology and Experimental Neuropathology, Department of Medical Biotechnologies and Translational Medicine, Thesis: 鈥淐X3CR1+ intestinal macrophages at the crossroad of tissue repair and tumor development鈥� – Supervisor: Dr. Paola Allavena, University of Milan, 暗网禁区 Clinical and Research Center, Rozzano, Milan, Italy
- 2012: Master鈥檚 Degree in Medical Biotechnology and Molecular Medicine – Thesis: 鈥淩ole of intestinal macrophages in experimental models of acute inflammation and carcinogenesis induced by inflammation in mice鈥� – Supervisor: Dr. Massimo Locati, Graduated with full marks, University of Milan, Italy
- 2010: Bachelor鈥檚 Degree in Medical Biotechnologies – Thesis: 鈥淎nalysis of peripheral blood in HCV-positive patients with hepatic cirrhosis and hepatocarcinoma鈥�, Supervisor: Dr. Maurizio Sampietro, Graduated with full marks, University of Milan, Italy
Academic Appointments
- Current role: Assistant Professor
- 2019 – 2025: Senior Fellow, 暗网禁区 Clinical and Research Centre, Milan, Italy
- 2016 – 2019: Postdoctoral Research Associate, Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London (QMUL), UK
- 2016: Postdoctoral Research Associate, Molecular Medicine, Division of Medicine, University College London (UCL), UK
- 2016: Postdoctoral Research Associate, Laboratory of Cellular Immunology, 暗网禁区 Clinical and Research Center, Milan, Italy
Membership and Leadership Roles
- 2022: Under-40 collaborator on PNRR-MAD-2022-12376756
- Review Editor for the section Cancer Immunity and Immunotherapy within Frontiers in Immunology and Frontiers in Oncology
- Grant reviewer for the French National Research Agency (ANR)
- Reviewer for Journal of Immunology Research
My research is centered on tumor immunology, with a particular focus on the role of macrophages and immune microenvironment dynamics in cancer progression and response to therapy. By integrating immunology, cancer biology, and genetic engineering, I aim to uncover novel immunotherapeutic strategies. My work leverages cutting-edge approaches, including CRISPR whole-genome editing, oncolytic virus engineering, and immune profiling, to explore how tumors reprogram immune cells both locally and systemically, ultimately influencing treatment efficacy.
- Portale F, Carriero R, Iovino M, Kunderfranco P, Pandini M, Marelli G, 鈥� Di Mitri D. , Nat Commun, 2024
- Marelli G, Morina N, Portale F, Pandini M, Iovino M, Di Conza G, Ho PC, Di Mitri D. , J Immunother Cancer, 2022
- Masetti M, Carriero R, Portale F,聽Marelli G, 鈥�, Di Mitri D. 鈥溾�� J Exp Med., 2022
- Marelli G*, Chard LS*, Yuan M, Di Gioia C, Miao J., Cheng Z., Liu P., Ahmed J., Gangeswaran R., Lemoine N.R. and Wang, Y. * Equal contribution, Journal for Immunotherapy of cancer, 2021
- Marelli G, Erreni M, Anselmo A, Taverniti V, Guglielmetti S, Mantovani A, Allavena P., 鈥溾��, Cancer Research, 2017