Education
- 2007 – 2011: Research Fellow, Department of Anaesthesiology, Intensive Care and Dermatological Sciences, University of Milan. Director: Prof. Luciano Gattinoni
- 2004 – 2005: Research Fellow, Bioenergetics Laboratory, Wolfson Institute for Biomedical Research, University College London (UCL), London, UK. Director: Prof. Mervyn Singer
- 2002 – 2006: Specialisation School in Anaesthesia and Resuscitation, University of Milan
- 1994 – 2002: Degree in Medicine and Surgery, University of Milan
Other
- 2015 – 2018: Medical Director, specialist in Anaesthesia and Resuscitation, IRCCS Ca’ Granda Foundation, Ospedale Maggiore Policlinico di Milano. Working in Emergency Surgery and A&E. Director: Prof. Antonio Maria Pesenti
- 2012 – 2015: Medical Director, specialist in Anaesthesia and Resuscitation, IRCCS Ca’ Granda Foundation, Ospedale Maggiore Policlinico di Milano. Head of the 鈥淓mma Vecla鈥� General Resuscitation Unit, a national reference centre for acute respiratory failure. Director: Prof. Luciano Gattinoni
- 2006 – 2007: Medical Director, specialist in Anaesthesia and Resuscitation, IRCCS Ca’ Granda Foundation, Ospedale Maggiore Policlinico di Milano. Working in Emergency Surgery and the Accident and Emergency Department. Director: Prof. Luciano Gattinoni
Clinical and preclinical research: on the pathophysiology of acute respiratory distress syndrome (ARDS) and lung injury induced by mechanical ventilation (VILI); on the role of mitochondrial dysfunction in the pathogenesis of organ failure during critical illness or drug intoxication; on the pathogenesis of lactic acidosis; on extracorporeal membrane oxygenation (ECMO). Expert in microdialysis, tissue oxygenation monitoring, oxygraphy (mitochondrial oxygen consumption), spectrophotometry (mitochondrial enzyme activity) and respiratory mechanics (oesophageal pressure, transpulmonary pressure, stress and strain).
- Protti A, Andreis DT, Monti M, Santini A, Sparacino CC, Langer T, Votta E, Gatti S, Lombardi L, Leopardi O, Masson S, Cressoni M, Gattinoni L. Lung stress and strain during mechanical ventilation: any difference between statics and dynamics? Crit Care Med. 2013 Apr;41(4):1046-55.
- Protti A, Lecchi A, Fortunato F, Artoni A, Greppi N, Vecchio S, Fagiolari G, Moggio M, Comi GP, Mistraletti G, Lanticina B, Faraldi L, Gattinoni L. Metformin overdose causes platelet mitochondrial dysfunction in humans. Crit Care. 2012 Oct 3;16(5):R180.
- Protti A, Fortunato F, Monti M, Vecchio S, Gatti S, Comi GP, De Giuseppe R, Gattinoni L. Metformin overdose, but not lactic acidosis per se, inhibits oxygen consumption in pigs. Crit Care. 2012 May 8;16(3):R75.
- Protti A, Fortunato F, Caspani ML, Pluderi M, Lucchini V, Grimoldi N, Solimeno LP, Fagiolari G, Ciscato P, Zella SM, Moggio M, Comi GP, Gattinoni L. Mitochondrial changes in platelets are not related to those in skeletal muscle during human septic shock. PLoS One. 2014 May 1;9(5):e96205.
- Protti A, Fortunato F, Artoni A, Lecchi A, Motta G, Mistraletti G, Novembrino C, Comi GP, Gattinoni L. Platelet mitochondrial dysfunction in critically ill patients: comparison between sepsis and cardiogenic shock. Crit Care. 2015 Feb 11;19:39.
- Protti A, Cressoni M, Santini A, Langer T, Mietto C, Febres D, Chierichetti M, Coppola S, Conte G, Gatti S, Leopardi O, Masson S, Lombardi L, Lazzerini M, Rampoldi E, Cadringher P, Gattinoni L. Lung stress and strain during mechanical ventilation: any safe threshold? Am J Respir Crit Care Med. 2011 May 15;183(10):1354-62.