  {id:37023,date:2016-01-13T00:00:00,date_gmt:2016-01-13T00:00:00,guid:{rendered:https:\/\/www.hunimed.eu\/news\/top-10-scoperte-scientifiche-2015-secondo-mantovani\/},modified:2025-10-14T02:38:52,modified_gmt:2025-10-14T02:38:52,slug:top-10-scoperte-scientifiche-2015-secondo-mantovani,status:publish,type:post,link:https:\/\/www.hunimed.eu\/it\/news\/top-10-scoperte-scientifiche-2015-secondo-mantovani\/,title:{rendered:Le top 10 scoperte scientifiche 2015 per il Prof. Mantovani},content:{rendered:<p><img loading=\lazy\ decoding=\async\ class=\alignright wp-image-22925 size-medium\ src=\https:\/\/www.hunimed.eu\/wp-content\/uploads\/2016\/01\/ricerca4-300x199.jpg\ alt=\Science equipment\ width=\300\ height=\199\ \/>Il <strong>2015<\/strong> ha portato\u00a0importanti <strong>scoperte\u00a0scientifiche<\/strong>\u00a0nel campo della <strong>medicina<\/strong>.<\/p>\n<p>Ecco le <strong>10\u00a0pi\u00f9 significative<\/strong> secondo\u00a0il <strong><a href=\http:\/\/www.humanitas-research.org\/mantovani-alberto\/\ target=\_blank\ rel=\noopener noreferrer\>Alberto Mantovani<\/a><\/strong>, Direttore Scientifico di °µÍø½ûÇø e Professore di °µÍø½ûÇø University.<\/p>\n<ol>\n<li>L&#8217;<strong>Immunoterapia<\/strong>\u00a0per curare il\u00a0<strong>cancro<\/strong>: si \u00e8 capito che non \u00e8 importante solo la cellula tumorale, ma anche la nicchia ecologica (il\u00a0<strong>microambiente<\/strong>) in cui essa vive; nel\u00a0microambiente infatti, alcune cellule vengono \u201ccorrotte\u201d e le difese immunitarie vengono spente. Riattivando le difese con l\u2019immunoterapia il paziente pu\u00f2 reagire al tumore.<\/li>\n<li>Il\u00a0<strong>vaccino<\/strong>\u00a0contro l\u2019<strong>Ebola<\/strong>.<\/li>\n<li>La<strong> Trabectedina<\/strong>, un principio attivo che colpisce non solo la cellula tumorale, ma anche le cellule corrotte di cui al primo punto.<\/li>\n<li>La\u00a0confermata sicurezza del <strong>vaccino<\/strong>\u00a0contro il\u00a0<strong>morbillo<\/strong>.<\/li>\n<li>Il\u00a0<strong>principio antimalarico<\/strong>\u00a0(<strong>Nobel<\/strong> per la Medicina 2015 alla dottoressa\u00a0Youyou Tu).<\/li>\n<li>Lo studio del\u00a0<strong>microbioma,\u00a0<\/strong>l\u2019insieme di tutti i\u00a0virus, batteri e funghi\u00a0che vivono dentro di noi, capaci di educare le nostre difese immunitarie.<\/li>\n<li>I progressi nella conoscenza delle <strong>malattie autoimmuni<\/strong>, in particolare \u00e8 stato scoperto\u00a0un anticorpo in grado di bloccare alcune interleuchine, proteine prodotte dal sistema immunitario che aggrediscono\u00a0i pazienti affetti da artrite psoriasica. \u00a0\u00a0<\/li>\n<li>Una combinazione di due\u00a0<strong>antivirali<\/strong>\u00a0(sofosbuvir\u2013velpatasvir)\u00a0straordinariamente efficace <strong>contro l\u2019epatite C<\/strong>;\u00a0consentirebbe una riduzione del 70% del rischio di epatocarcinoma.\u00a0<\/li>\n<li>La potenza degli\u00a0<strong>anticorpi monoclonali <\/strong>(anticorpi in grado di legarsi ad una molecola-bersaglio):\u00a0secondo uno studio del 2015,\u00a0bloccando un recettore presente nel fegato con un anticorpo monoclonale si assiste a una <strong>riduzione dei livelli di colesterolo<\/strong>, sia in soggetti sani, sia in soggetti con alti livelli di colesterolo familiare.\u00a0<\/li>\n<li>La\u00a0<strong>memoria<\/strong>\u00a0dell\u2019<strong>immunit\u00e0 innata:<\/strong>\u00a0alcune infezioni (soprattutto intestinali) lasciano un\u2019impronta nel sistema immunitario innato e lo rendono pi\u00f9 sensibile a infezioni successive.\u00a0<\/li>\n<\/ol>\n<p>Vuoi saperne di pi\u00f9? Leggi l\u2019intervista completa sul\u00a0<strong><a href=\http:\/\/www.corriere.it\/extra-per-voi\/2015\/12\/24\/2015-medicina-scoperte-piu-importanti-secondo-alberto-mantovani-fd4ebbf8-a991-11e5-8f07-76e7bd2ba963.shtml\>Corriere<\/a><\/strong>.<\/p>\n<p><em>Fonte: \u201cExtra\u201d, speciale del Corriere della Sera.<\/em><\/p>\n,protected:false},excerpt:{rendered:<p>Il 2015 ha portato\u00a0importanti scoperte\u00a0scientifiche\u00a0nel campo della medicina. Ecco le 10\u00a0pi\u00f9 significative secondo\u00a0il Alberto Mantovani, Direttore Scientifico di °µÍø½ûÇø e Professore di °µÍø½ûÇø University. L&#8217;Immunoterapia\u00a0per curare il\u00a0cancro: si \u00e8 capito che non \u00e8 importante solo la cellula tumorale, ma anche la nicchia ecologica (il\u00a0microambiente) in cui essa vive; nel\u00a0microambiente infatti, alcune cellule vengono \u201ccorrotte\u201d e [&hellip;]<\/p>\n,protected:false},author:1,featured_media:14494,comment_status:open,ping_status:open,sticky:false,template:,format:standard,meta:{_acf_changed:false,_kad_blocks_custom_css:,_kad_blocks_head_custom_js:,_kad_blocks_body_custom_js:,_kad_blocks_footer_custom_js:,footnotes:},categories:[1673,401,2025,2385],tags:[414,2421],class_list:[post-37023,post,type-post,status-publish,format-standard,has-post-thumbnail,hentry,category-medical-sciences-2,category-mondo-humanitas,category-scienze-mediche-3-2,category-tutti-5,tag-alberto-mantovani,tag-scoperte-scientifiche-5],acf:[],yoast_head:<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Le 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