{id:11748,date:2025-03-12T10:19:01,date_gmt:2025-03-12T10:19:01,guid:{rendered:http:\/\/hunimed-new.local\/Member\/giulia-marelli-2\/},modified:2026-03-31T13:18:30,modified_gmt:2026-03-31T13:18:30,slug:giulia-marelli,status:publish,type:member,link:https:\/\/www.hunimed.eu\/it\/member\/giulia-marelli\/,title:{rendered:Giulia Marelli},content:{rendered:\n<div class=\wp-block-hunimed-tabs-content hunimed-tabs-content-block\><div class=\tabs-container\>\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Biosketch\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Biosketch<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<p><strong>Formazione<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li><strong>2012 &#8211; 2016<\/strong>: Dottorato in Patologia e Neuropatologia Sperimentali &#8211; Dipartimento di Biotecnologie Mediche e Medicina Traslazionale, Tesi: &#8220;CX3CR1+ intestinal macrophages at the crossroad of tissue repair and tumor development&#8221;, Supervisore: Dr.ssa Paola Allavena &#8211; Universit\u00e0 di Milano, °µÍø½ûÇø Clinical and Research Center, Milano<\/li>\n\n\n\n<li><strong>2012<\/strong>: Laurea Magistrale in Biotecnologie Mediche e Medicina Molecolare &#8211; Tesi: &#8220;Role of intestinal macrophages in experimental models of acute inflammation and carcinogenesis induced by inflammation in mice&#8221;, Supervisore: Dr. Massimo Locati &#8211; Laurea conseguita con il massimo dei voti, Universit\u00e0 di Milano, Italia<\/li>\n\n\n\n<li><strong>2010<\/strong>: Laurea Triennale in Biotecnologie Mediche &#8211; Tesi: &#8220;Analisi del sangue periferico in pazienti HCV-positivi con cirrosi epatica ed epatocarcinoma&#8221;, Supervisore: Dr. Maurizio Sampietro &#8211; Laurea conseguita con il massimo dei voti, Universit\u00e0 di Milano, Italia<\/li>\n<\/ul>\n\n\n\n<p><strong>Incarichi Accademici<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li><strong>Ruolo attuale<\/strong>: Ricercatore a tempo determinato di tipo A<\/li>\n\n\n\n<li><strong>2019 &#8211; 2025<\/strong>: Senior Fellow, °µÍø½ûÇø Clinical and Research Centre, Milano, Italia<\/li>\n\n\n\n<li><strong>2016 &#8211; 2019<\/strong>: Ricercatore Post-Dottorato, Centre for Molecular Oncology, Barts Cancer Institute, QMUL, Regno Unito<\/li>\n\n\n\n<li><strong>2016<\/strong>: Ricercatore Post-Dottorato, Molecular Medicine, Division of Medicine, University College London, Regno Unito<\/li>\n\n\n\n<li><strong>2016<\/strong>: Ricercatore Post-Dottorato, Laboratorio di Immunologia Cellulare, °µÍø½ûÇø Clinical and Research Center, Milano, Italia<\/li>\n<\/ul>\n\n\n\n<p><strong>Affiliazioni<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li><strong>2022<\/strong>: Collaboratore Under-40 per PNRR-MAD-2022-12376756<\/li>\n\n\n\n<li>Editore Revisore per la sezione Cancer Immunity and Immunotherapy, Frontiers in Immunology e Frontiers in Oncology<\/li>\n\n\n\n<li>Revisore per il finanziamento di progetti della French National Research Agency (ANR)<\/li>\n\n\n\n<li>Revisore per il Journal of Immunology Research<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Ricerca\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Ricerca<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<p>La mia ricerca si concentra sull&#8217;immunologia tumorale, con particolare attenzione al ruolo dei macrofagi e alle dinamiche del microambiente immunitario nella progressione del cancro e nella risposta alla terapia. Integrando immunologia, biologia del cancro e ingegneria genetica, il mio obiettivo \u00e8 scoprire nuove strategie immunoterapeutiche. Il mio lavoro sfrutta approcci all&#8217;avanguardia, tra cui l&#8217;editing genomico CRISPR, l&#8217;ingegneria di virus oncolitici e il profiling immunologico, per studiare come i tumori riprogrammino le cellule immunitarie sia localmente che a livello sistemico, influenzando cos\u00ec l&#8217;efficacia dei trattamenti.<\/p>\n<\/div><\/div><\/div>\n\n\n\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Pubblicazioni\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Pubblicazioni<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<ol class=\wp-block-list\>\n<li>Portale F, Carriero R, Iovino M, Kunderfranco P, Pandini M, <strong>Marelli G<\/strong>, \u2026 Di Mitri D. <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/39609420\/\>\u201cC\/EBP\u03b2-dependent autophagy inhibition hinders NK cell function in cancer\u201d<\/a>, Nat Commun, 2024<\/li>\n\n\n\n<li><strong>Marelli G<\/strong>, Morina N, Portale F, Pandini M, Iovino M, Di Conza G, Ho PC, Di Mitri D. <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/35798535\/\>\u201cLipid-loaded macrophages as new therapeutic target in cancer\u201d<\/a>, J Immunother Cancer, 2022<\/li>\n\n\n\n<li>Masetti M, Carriero R, Portale F,\u00a0<strong>Marelli G<\/strong>, \u2026, Di Mitri D. \u201c<a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/34919143\/\>Lipid-loaded tumor-associated macrophages sustain tumor growth and invasiveness in prostate cancer.<\/a>\u201c J Exp Med., 2022<\/li>\n\n\n\n<li><strong>Marelli G<\/strong>*, Chard LS*, Yuan M, Di Gioia C, Miao J., Cheng Z., Liu P., Ahmed J., Gangeswaran R., Lemoine N.R. and Wang, Y. <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/33500259\/\>\u201cA systemically deliverable Vaccinia virus with increased capacity for inter- and intra-tumoral spread effectively treats pancreatic cancer\u201d<\/a> * Equal contribution, Journal for Immunotherapy of cancer, 2021<\/li>\n\n\n\n<li><strong>Marelli G<\/strong>, Erreni M, Anselmo A, Taverniti V, Guglielmetti S, Mantovani A, Allavena P., \u201c<a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/28619710\/\>Heme Oxygenase-1 production by intestinal CX3CR1+ macrophages, promotes resolution of inflammation and protects against carcinogenesis<\/a>\u201d, Cancer Research, 2017<\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div>\n,protected:false},excerpt:{rendered:,protected:false},featured_media:32883,template:,departaments:[250,3470],roles:[214,347],class_list:[post-11748,member,type-member,status-publish,has-post-thumbnail,hentry,departament-istologia-2,departament-istologia-ed-embriologia-umana,role-ricercatore-2,role-ricercatore-3],acf:[],yoast_head:<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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