{id:11685,date:2024-02-21T07:47:49,date_gmt:2024-02-21T07:47:49,guid:{rendered:http:\/\/hunimed-new.local\/Member\/vincenzo-ronca-2\/},modified:2026-04-01T10:03:20,modified_gmt:2026-04-01T10:03:20,slug:vincenzo-ronca,status:publish,type:member,link:https:\/\/www.hunimed.eu\/it\/member\/vincenzo-ronca\/,title:{rendered:Vincenzo Ronca},content:{rendered:\n<div class=\wp-block-hunimed-tabs-content hunimed-tabs-content-block\><div class=\tabs-container\>\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Biosketch\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Biosketch<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<p><strong>Formazione<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li><strong>2020 &#8211; 2024<\/strong>: Joint PhD Program in Immunology and Immunotherapy and Translational Medicine, University of Birmingham, and University of Milano-Bicocca, Milan, Italy<\/li>\n\n\n\n<li><strong>2022 &#8211; 2023<\/strong>: Master di secondo livello in \u201cEpatologia avanzata e Medicina dei Trapianti\u201d Universit\u00e0 di Milano-Bicocca, Universit\u00e0 di Padova, Italia<\/li>\n\n\n\n<li><strong>2015 &#8211; 2020<\/strong>: Specializzazione in Medicina Intenrna 70\/70 cum laude<\/li>\n\n\n\n<li><strong>2008 &#8211; 2014<\/strong>: Laurea in Medicina e Chirurgia, summa cum Laude (110\/110 cum laude ed encomio della commissione \u2013 summa cum laude) Universit\u00e0 di Pavia<\/li>\n<\/ul>\n\n\n\n<p><strong>Incarichi Accademici<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li>Ruolo accademico attuale \u2013 Ricercatore a tempo determinato di tipo B (tenure track \u2013 RTDB)<\/li>\n\n\n\n<li><strong>2022 &#8211; 2023<\/strong>: Visiting Research Fellow Immunology Frontier Research Centre, Osaka University, Japan \u2013 Shimon Sakaguchi\u2019s lab<\/li>\n\n\n\n<li><strong>2019 &#8211; 2023<\/strong>: Fellow at Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, and Liver Unit Queen Elizabeth Hospital University of Birmingham (UK)<\/li>\n\n\n\n<li><strong>2016 &#8211; 2019<\/strong>: Clinical and Research Fellow at Division of Gastroenterology and Centre for Autoimmune Liver Diseases at University of Milan-Bicocca School of Medicine, Monza (Italy)<\/li>\n\n\n\n<li><strong>2014 &#8211; 2016<\/strong>: Research Fellow at Centre for Autoimmune Liver Diseases, °µÍø½ûÇø University, Milan (Italy)<\/li>\n<\/ul>\n\n\n\n<p><strong>Affiliazioni<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li>ERN Rare liver \u2013 Lead of Autoimmune hepatitis special group<\/li>\n\n\n\n<li><strong>2023<\/strong>: Membro &#8211; American Association for the study of liver diseases (AASLD)<\/li>\n\n\n\n<li><strong>2022<\/strong>: Membro &#8211; International Primary Sclerosing Cholangitis group<\/li>\n\n\n\n<li><strong>2019<\/strong>: General Medical Council, Specialist Register (number: 7693775)<\/li>\n\n\n\n<li><strong>2018<\/strong>: Membro &#8211; International Primary Biliary Cholangitis Study group (GLOBE)<\/li>\n\n\n\n<li><strong>2015<\/strong>: Membro &#8211; International Autoimmune Hepatitis Group<\/li>\n\n\n\n<li><strong>2015<\/strong>: Membro &#8211; European Association for the Study of the Liver (EASL)<\/li>\n\n\n\n<li><strong>2014<\/strong>: Membro &#8211; Associazione italiana studio fegato (AISF)<\/li>\n<\/ul>\n\n\n\n<p><strong>Premi e Onorificenze<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li>NIHR Academic Clinical Fellowship in Gastroenterology, Liver Unit and Institute of Immunology and Immunotherapy, University of Birmingham UK<\/li>\n\n\n\n<li><strong>2023<\/strong>: AISF Premio come migliore presentazione orale<\/li>\n\n\n\n<li><strong>2020 \u2013 2023<\/strong>: Juan Rodes EASL Fellowship<\/li>\n\n\n\n<li><strong>2021<\/strong>: EMBO short-term fellowship<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Ricerca\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Ricerca<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<p>Il Dr. Ronca \u00e8 un epatologo la cui principale area di competenza \u00e8 rappresentata dalle malattie autoimmuni del fegato e dall&#8217;immunotolleranza. Ha conseguito la laurea in medicina presso l&#8217;Universit\u00e0 di Pavia (Summa cum laude) e un master in epatologia avanzata e medicina dei trapianti presso l&#8217;Universit\u00e0 di Milano Bicocca.<\/p>\n\n\n\n<p>La carriera di ricerca del Dr. Ronca \u00e8 iniziata concentrandosi sulla stratificazione del rischio e l&#8217;epidemiologia delle malattie biliari e sul trattamento chirurgico dell&#8217;epatocarcinoma. Si \u00e8 trasferito nel Regno Unito nel 2019 come research fellow ed \u00e8 stato premiato con una fellowship NIHR per studiare il ruolo delle cellule T regolatorie (Tregs) nella colangite biliare primitiva (PBC).<\/p>\n\n\n\n<p>Durante la sua fellowship, ha collaborato alla progettazione e all&#8217;esecuzione di una sperimentazione clinica basata sulla terapia cellulare utilizzando Tregs autologhe nella PBC (sperimentazione attualmente in corso). I suoi studi di dottorato sono stati condotti presso l&#8217;Universit\u00e0 di Birmingham, finanziati da una Juan Rodes Fellowship dell&#8217;Associazione Europea per lo Studio del Fegato. La sua ricerca si \u00e8 concentrata su a) il crosstalk tra epitelio biliare e cellule T e b) l&#8217;immunotolleranza con un forte focus sulla biologia delle cellule T regolatorie. Ha descritto una nuova struttura cellula-in-cellula e un meccanismo di danno dell&#8217;epitelio biliare, in cui una popolazione di cellule T CD8+ che esprimono E-caderina invade il citoplasma delle cellule epiteliali biliari.<\/p>\n\n\n\n<p>Nel 2021, si \u00e8 unito al laboratorio di Shimon Sakaguchi presso l&#8217;Universit\u00e0 di Osaka (Giappone) dopo aver ricevuto una fellowship EMBO, con l&#8217;obiettivo di sviluppare nuove strategie per produrre cellule Treg indotte e stabili specifiche per l&#8217;antigene come strumento terapeutico per le malattie autoimmuni.<\/p>\n\n\n\n<p>Nel dicembre 2023, il Dr. Ronca \u00e8 tornato in Italia per unirsi all&#8217;Universit\u00e0 °µÍø½ûÇø come Ricercatore (RTDB) in Medicina Interna ed assistente epatologo. Si \u00e8 unito al laboratorio di immunopatologia epatobiliare diretto dalla Prof.ssa Ana Lleo e all&#8217;Unit\u00e0 di Medicina Interna. Il suo lavoro attuale \u00e8 focalizzato sugli aspetti clinici e patogenetici delle malattie autoimmuni del fegato.<\/p>\n\n\n\n<p>Principali aree di ricerca:<\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li>Immunologia del fegato<\/li>\n\n\n\n<li>Malattie autoimmuni del fegato<\/li>\n\n\n\n<li>Immunotolleranza e biologia delle cellule T regolatorie<\/li>\n\n\n\n<li>Colestasi ed acidi biliari<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Pubblicazioni\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Pubblicazioni<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<ol class=\wp-block-list\>\n<li>Montano-Loza AJ, <strong>Ronca V<\/strong>, et al. <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/35143897\/\>Risk factors and outcomes associated with recurrent autoimmune hepatitis following liver transplantation<\/a>. J Hepatol. 2022 Jul;77(1):84-97. doi: 10.1016\/j.jhep.2022.01.022. Epub 2022 Feb 8. PMID: 35143897.<\/li>\n\n\n\n<li>Davies, S.P*., <strong>Ronca, V<\/strong>*., Wootton, G.E. et al. <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/38286990\/\>Expression of E-cadherin by CD8+ T cells promote their invasion into biliary epithelial cells<\/a>. Nat Commun 15, 853 (2024). https:\/\/doi.org\/10.1038\/s41467- 024-44910-2+ T cells promote their invasion into biliary epithelial cells. Nat Comm Nov 2023.<\/li>\n\n\n\n<li><strong>Ronca V<\/strong>, Barabino M, Santambrogio R, Opocher E, Hodson J, Bertolini E, Birocchi S, Piccolo G, Battezzati P, Cattaneo M, Podda GM. <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/34716696\/\>Impact of Platelet Count on Perioperative Bleeding in Patients with Cirrhosis Undergoing Surgical Treatments of Liver Cancer<\/a>. Hepatol Commun. 2022 Feb;6(2):423- 434. doi: 10.1002\/hep4.1806. Epub 2021 Oct 30. PMID: 34716696; PMCID: PMC8793986.<\/li>\n\n\n\n<li><strong>Ronca V<\/strong>, Wootton G, Milani C, Cain O. <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/32983177\/\>The Immunological Basis of Liver Allograft Rejection<\/a>. Front Immunol. 2020 Sep 2; 11:2155. doi: 10.3389\/fimmu.2020.02155. PMID: 32983177; PMCID: PMC7492390.<\/li>\n\n\n\n<li><strong>Ronca V<\/strong>, Chen QB, Lygoura V, Ben-Mustapha I, Shums Z, Trifa M, Carbone M, Mancuso C, Milani C, Bernuzzi F, Ma X, Agrebi N, Norman GL, Chang C, Gershwin ME, Barbouche MR, Invernizzi P. <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/31111679\/\>Autoantibodies in patients with interleukin 12 receptor beta 1 deficiency<\/a>. J Dig Dis. 2019 Jul;20(7):363- 370. doi: 10.1111\/1751-2980.12790. Epub 2019 Jul 10. PMID: 31111679.<\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div>\n,protected:false},excerpt:{rendered:,protected:false},featured_media:32937,template:,departaments:[251],roles:[214],class_list:[post-11685,member,type-member,status-publish,has-post-thumbnail,hentry,departament-medicina-interna,role-ricercatore-2],acf:[],yoast_head:<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Vincenzo Ronca - Hunimed<\/title>\n<meta name=\description\ content=\Biosketch Formazione 2020 - 2024: Joint PhD Program in Immunology and Immunotherapy and Translational Medicine, University of Birmingham, and University\ \/>\n<meta name=\robots\ content=\index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\ \/>\n<link rel=\canonical\ href=\https:\/\/www.hunimed.eu\/it\/member\/vincenzo-ronca\/\ \/>\n<meta property=\og:locale\ content=\it_IT\ \/>\n<meta property=\og:type\ content=\article\ \/>\n<meta property=\og:title\ content=\Vincenzo Ronca - 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