{id:11550,date:2021-04-01T08:29:39,date_gmt:2021-04-01T08:29:39,guid:{rendered:http:\/\/hunimed-new.local\/Member\/nicoletta-di-simone-2\/},modified:2026-03-30T14:29:19,modified_gmt:2026-03-30T14:29:19,slug:nicoletta-di-simone,status:publish,type:member,link:https:\/\/www.hunimed.eu\/it\/member\/nicoletta-di-simone\/,title:{rendered:Nicoletta Di Simone},content:{rendered:\n<div class=\wp-block-hunimed-tabs-content hunimed-tabs-content-block\><div class=\tabs-container\>\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Biosketch\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Biosketch<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<p><strong>Formazione<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li><strong>1998<\/strong>: Dottorato di Ricerca in Scienze Ostetriche e Ginecologiche, Universit\u00e0 La Sapienza di Roma<\/li>\n\n\n\n<li><strong>1994 &#8211; 1996<\/strong>: Borsa di studio presso il Centro Nazionale per la Ricerca sull&#8217;Infertilit\u00e0 del Massachusetts General Hospital \u2013 Harvard Medical School, Boston, USA<\/li>\n\n\n\n<li><strong>1994 &#8211; 1996<\/strong>: Fellowship al National Center for Infertility Research del Massachusetts General Hospital \u2013 Harvard Medical School, Boston, USA<\/li>\n\n\n\n<li><strong>1992<\/strong>: Specializzazione in Ginecologia ed Ostetricia, Universit\u00e0 Cattolica del Sacro Cuore, Roma<\/li>\n\n\n\n<li><strong>1988<\/strong>: Laurea in Medicina e Chirurgia, Universit\u00e0 Cattolica del Sacro Cuore, Roma<\/li>\n<\/ul>\n\n\n\n<p><strong>Incarichi Accademici<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li><strong>2021<\/strong>: Professore di Prima Fascia di Ginecologia e Ostetricia, °µÍø½ûÇø University Milano<\/li>\n\n\n\n<li><strong>2021<\/strong>: Direttore della Scuola di Specializzazione in Ginecologia e Ostetricia, °µÍø½ûÇø University<\/li>\n\n\n\n<li><strong>2017<\/strong>: Abilitazione Nazionale a Professore di Prima Fascia<\/li>\n\n\n\n<li><strong>2007<\/strong>: Professore Associato di Ginecologia ed Ostetricia, Facolt\u00e0 di Medicina e Chirurgia, Universit\u00e0 Cattolica del Sacro Cuore, Roma<\/li>\n\n\n\n<li><strong>2002<\/strong>: Ricercatore Universitario, Ginecologia ed Ostetricia, Facolt\u00e0 di Medicina e Chirurgia, Universit\u00e0 Cattolica del Sacro Cuore, Roma<\/li>\n\n\n\n<li><strong>2001<\/strong>: Visiting Professor, presso la Prenatal Medicine Research Unit, Universit\u00e4ts Frauenklinik, Kantonsspital, Basel, Switzerland<\/li>\n<\/ul>\n\n\n\n<p><strong>Affiliazioni<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li><strong>2019<\/strong>: Membro Eletto del Consiglio Direttivo della Fondazione Vaticana, Istituto Scientifico Internazionale (ISI) Paolo VI<\/li>\n\n\n\n<li><strong>2008<\/strong>: Membro Eletto Society of Reproductive Investigation (SRI)<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Ricerca\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Ricerca<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<p>L\u2019attivita\u2019 di ricerca sviluppata ha permesso di comprendere numerose cause che determinano un insuccesso ostetrico (dal mancato concepimento all\u2019abortivita\u2019 ricorrente, il parto prematuro e&nbsp; le complicanze materne) con un miglioramento del trattamento.<\/p>\n\n\n\n<p>Elenco di alcuni temi sviluppati:<\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li>Abortivit\u00e0 spontanea ricorrente e terapia<\/li>\n\n\n\n<li>Il ruolo del morbo celiaco nelle problematiche di salute della donna e le complicanze ostetriche ad esso associate<\/li>\n\n\n\n<li>L\u2019infiammazione endometriale<\/li>\n\n\n\n<li>Le cause di preeclampsia e i markers predittivi di patologia<\/li>\n\n\n\n<li>Il ruolo di una regolare funzionalita\u2019\/permeabilita\u2019 intestinale nella gravidanza<\/li>\n\n\n\n<li>L\u2019 utilizzo del microbiota come strumento diagnostico e terapeutico per la donna<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Pubblicazioni\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Pubblicazioni<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<ol class=\wp-block-list\>\n<li><a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/33193302\/\>Recent Insights on the Maternal Microbiota: Impact on Pregnancy Outcomes<\/a>, <strong>N.Di Simone,<\/strong> A. Santamaria Ortiz, M. Specchia, C. Tersigni, P. Villa, A. Gasbarrini, G. Scambia, S. D\u2019 Ippolito. Front Immunol. 2020 Oct 23;11:528202. doi: 10.3389\/fimmu.2020.528202. eCollection 2020<\/li>\n\n\n\n<li><a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/32511256\/?from_term=di+simone+n&amp;from_filter=ds1.y_1&amp;from_pos=10\>Synthetic PreImplantation Factor (sPIF) reduces inflammation and prevents preterm birth. <\/a>Spinelli M, Boucard C, Di Nicuolo F, Haesler V, Castellani R, Pontecorvi A, Scambia G, Granieri C, Barnea ER, Surbek D, Mueller M, <strong>N. Di Simone<\/strong>&nbsp;PLoS One. 2020 Jun 8;15(6):e0232493. doi: 10.1371\/journal.pone.0232493. eCollection 2020.<\/li>\n\n\n\n<li><a href=\http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27484400\>Helicobacter pylori infection contributes to placental impairment in preeclampsia: basic and clinical evidences.<\/a> <strong>N. Di Simone,<\/strong> Tersigni C, Cardaropoli S, Franceschi F, Di Nicuolo F, Castellani R, Bugli F, de Waure C, Cavaliere AF, Gasbarrini A, Sanguinetti M, Scambia G, Todros T. Helicobacter. 2017 Apr;22(2). doi: 10.1111\/hel.12347. Epub 2016 Aug 3.<\/li>\n\n\n\n<li><a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/26883458\/\>Human leukocyte antigen (HLA) DQ2\/DQ8 prevalence in recurrent pregnancy loss women<\/a>. D\u2019 Ippolito S, Gasbarrini A, Castellani R, Rocchetti S, Sisti LG, Scambia G, <strong>N. Di Simone,<\/strong>\u00a0Autoimmun Rev. 2016 Jul;15(7):638-43. doi: 10.1016\/j.autrev.2016.02.009. Epub 2016 Feb 13.<\/li>\n\n\n\n<li><a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/26474737\/\>Inflammosome in the human endometrium:further step in the evaluation of the \u201cmaternal side\u201d.<\/a> D\u2019Ippolito S, Tersigni C, Marana R, Di Nicuolo F, Gaglione R, Rossi ED, Castellani R, Scambia G, <strong>N. Di Simone.<\/strong>\u00a0Fertil Steril. 2016 Jan;105(1):111-8.e1-4. doi: 10.1016\/j.fertnstert.2015.09.027. Epub 2015 Oct 30.<\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div>\n,protected:false},excerpt:{rendered:,protected:false},featured_media:49059,template:,departaments:[281,277],roles:[203,209],class_list:[post-11550,member,type-member,status-publish,has-post-thumbnail,hentry,departament-ginecologia-e-ostetricia-2,departament-ostetricia-e-ginecologia-2,role-full-professor-it,role-professore-ordinario-2],acf:[],yoast_head:<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nicoletta Di Simone - Hunimed<\/title>\n<meta name=\description\ content=\Biosketch Formazione 1998: Dottorato di Ricerca in Scienze Ostetriche e Ginecologiche, Universit\u00e0 La Sapienza di Roma 1994 - 1996: Borsa di studio presso\ \/>\n<meta name=\robots\ content=\index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\ \/>\n<link rel=\canonical\ href=\https:\/\/www.hunimed.eu\/it\/member\/nicoletta-di-simone\/\ \/>\n<meta property=\og:locale\ content=\it_IT\ \/>\n<meta property=\og:type\ content=\article\ \/>\n<meta property=\og:title\ content=\Nicoletta Di Simone - 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