{id:11518,date:2020-01-31T13:58:34,date_gmt:2020-01-31T13:58:34,guid:{rendered:http:\/\/hunimed-new.local\/Member\/maria-laura-costantino-2\/},modified:2026-03-30T13:38:45,modified_gmt:2026-03-30T13:38:45,slug:maria-laura-costantino,status:publish,type:member,link:https:\/\/www.hunimed.eu\/it\/member\/maria-laura-costantino\/,title:{rendered:Maria Laura Costantino},content:{rendered:\n<div class=\wp-block-hunimed-tabs-content hunimed-tabs-content-block\><div class=\tabs-container\>\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Biosketch\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Biosketch<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<p><strong>Formazione<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li>Dottorato di Ricerca in Bioingegneria<\/li>\n\n\n\n<li>Laurea in Ingegneria Meccanica<\/li>\n<\/ul>\n\n\n\n<p><strong>Incarichi Accademici<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li><strong>2013 &#8211; 2018<\/strong>: Coordinatore del Consiglio di Corso di Studi in Ingegneria Biomedica (Laurea e Laurea Magistrale) del Politecnico di Milano e Membro della Giunta della Scuola di Ingegneria Industriale e dell\u2019Informazione dello stesso Politecnico<\/li>\n\n\n\n<li><strong>da met\u00e0 &#8217;90<\/strong>: Direttore del Laboratorio di Organi Artificiali, parte del Laboratorio di Meccanica delle Strutture Biologiche (LaBS) del Politecnico di Milano, con coordinamento delle attivit\u00e0 di ricerca, didattica e consulenza<\/li>\n\n\n\n<li>Membro del Consiglio del Dottorato di Ricerca in Bioingegneria del Politecnico di Milano<\/li>\n<\/ul>\n\n\n\n<p><strong>Affiliazioni<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li>Membro dell&#8217;European Society of Artificial Organs (ESAO)<\/li>\n\n\n\n<li>Membro dell&#8217;American Society for Artificial Internal Organs (ASAIO)<\/li>\n\n\n\n<li>Membro dell&#8217;European Society of Biomechanics (ESB)<\/li>\n\n\n\n<li>Membro della National Bioengineering Society (GNB)<\/li>\n<\/ul>\n\n\n\n<p><strong>Altro<\/strong><\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li><strong>2007 &#8211; 2013:<\/strong> Responsabile, o Partner, di progetti di ricerca totalmente o parzialmente finanziati da istituzioni pubbliche o private; tra questi il progetto di ricerca \u201cDialysIS (Dialysis therapy between Italy and Switzerland)\u201d, finanziato nell\u2019ambito del Programma INTERREG Italia \u2013 Svizzera<\/li>\n\n\n\n<li>Responsabile di contratti di ricerca o consulenza con aziende italiane, europee o americane nel campo biomedico<\/li>\n\n\n\n<li>Co-titolare di brevetti europei relativi a dispositivi biomedici<\/li>\n\n\n\n<li>Revisore per riviste scientifiche internazionali, tra le quali <em>The International Journal of Artificial Organs<\/em>, <em>ASAIO Journal<\/em>, <em>Artificial Organs<\/em>, <em>ASME Journal<\/em>, <em>Journal of Applied Biomaterials and Biomechanics<\/em>, <em>Journal of Biomechanics<\/em><\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Ricerca\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Ricerca<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<p>L\u2019attivit\u00e0 di ricerca \u00e8 da sempre radicata nel campo della Bioingegneria Industriale (teorica e sperimentale) con particolare riferimento a:<\/p>\n\n\n\n<ul class=\wp-block-list\>\n<li>Studio del trasporto di massa e di energia, e della fluidodinamica nei sistemi biologici e negli organi artificiali tramite sia modellazione computazionale sia valutazione sperimentale.<\/li>\n\n\n\n<li>Modellazione matematica dell\u2019interazione macchina-paziente.<\/li>\n\n\n\n<li>Sviluppo di modelli paziente-specifici volti a prevedere e ottimizzare la risposta del singolo paziente al trattamento terapeutico, supportati dall\u2019analisi strutturata di dati clinici.<\/li>\n\n\n\n<li>Progettazione e sperimentazione di dispositivi e apparecchiature biomedicali (es. ventricoli per assistenza cardiaca (VAD), filtra e sistemi per emodialisi, ossigenatori per il sangue, sistemi pompanti, protesi valvolari cardiache, circuiti e componenti per la circolazione extracorporea, sistemi per la ventilazione liquida di neonati premature e a termine, ecc.).<\/li>\n\n\n\n<li>Sviluppo di nuovi metodi per il trasporto e il rilascio controllato di farmaci.<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Pubblicazioni\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Pubblicazioni<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<ol class=\wp-block-list\>\n<li>Possenti L., Casagrande G, Di Gregorio S., Zunino P., <strong><strong>Costantino ML<\/strong><\/strong> (2019). <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/30448400\/\>Numerical simulations of the microvascular fluid balance with a non-linear model of the lymphatic system<\/a>. DOI:10.1016\/j.mvr.2018.11.003. MICROVASCULAR RESEARCH, vol. 122, p. 101-110, ISSN: 0026-2862.<\/li>\n\n\n\n<li>Piergiovanni M., Casagrande G., Taverna F., Corridori I., Frigerio M., Bianchi E., Arienti F., Mazzocchi A., Dubini G., <strong>Costantino ML<\/strong> (2019). <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/31410713\/\>Shear-Induced Encapsulation into Red Blood Cells: A New Microfluidic Approach to Drug Delivery<\/a>. DOI:10.1007\/s10439-019-02342-w. ANNALS OF BIOMEDICAL ENGINEERING, vol. 2019 Aug 13, p. 1-11, ISSN: 0090-6964.<\/li>\n\n\n\n<li>Bianchi C., Lanzarone E., Casagrande G., <strong>Costantino ML<\/strong> (2018). <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/29325494\/\>A Bayesian approach for the identification of patient-specific parameters in a dialysis kinetic model<\/a>. DOI:10.1177\/0962280217745572. STATISTICAL METHODS IN MEDICAL RESEARCH, p. 1-27, ISSN: 0962-2802.<\/li>\n\n\n\n<li>Luraghi G., Wu Wei, De Gaetano F., Rodriguez M., Jose F., Moggridge Geoff D., Serrani M., Stasiak J., <strong><strong>Costantino ML<\/strong>,<\/strong> Migliavacca F. (2017). <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/28454910\/\>Evaluation of an aortic valve prosthesis: Fluid-structure interaction or structural simulation?<\/a> DOI:10.1016\/j.jbiomech.2017.04.004. JOURNAL OF BIOMECHANICS, vol. 58, p. 45-51, ISSN: 0021-9290.<\/li>\n\n\n\n<li>Casagrande G., Bianchi C., Vito D., Carfagna F., Minoretti C., Pontoriero G., Rombol\u00e0 G., Schoenholzer C., <strong>Costantino ML<\/strong> (2016). <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/27338283\/\>Patient-specific modeling of multicompartmental fluid and mass exchange during dialysis<\/a>. DOI:10.5301\/ijao.5000504. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, vol. 39 (5), pp.220-227, ISSN:0391-3988.<\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div>\n,protected:false},excerpt:{rendered:,protected:false},featured_media:32563,template:,departaments:[266,363],roles:[203,206],class_list:[post-11518,member,type-member,status-publish,has-post-thumbnail,hentry,departament-bioingegneria-industriale-2,departament-bioingegneria-industriale-4,role-full-professor-it,role-professore-ordinario],acf:[],yoast_head:<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Maria Laura Costantino - Hunimed<\/title>\n<meta name=\description\ content=\Biosketch Formazione Dottorato di Ricerca in Bioingegneria Laurea in Ingegneria Meccanica Incarichi Accademici 2013 - 2018: Coordinatore del Consiglio di\ \/>\n<meta name=\robots\ content=\index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\ \/>\n<link rel=\canonical\ href=\https:\/\/www.hunimed.eu\/it\/member\/maria-laura-costantino\/\ \/>\n<meta property=\og:locale\ content=\it_IT\ \/>\n<meta property=\og:type\ content=\article\ \/>\n<meta property=\og:title\ content=\Maria Laura Costantino - 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