{id:11480,date:2019-11-23T16:47:08,date_gmt:2019-11-23T16:47:08,guid:{rendered:http:\/\/hunimed-new.local\/Member\/raffaella-bonecchi-2\/},modified:2026-03-30T10:03:28,modified_gmt:2026-03-30T10:03:28,slug:raffaella-bonecchi,status:publish,type:member,link:https:\/\/www.hunimed.eu\/it\/member\/raffaella-bonecchi\/,title:{rendered:Raffaella Bonecchi},content:{rendered:\n<div class=\wp-block-hunimed-tabs-content hunimed-tabs-content-block\><div class=\tabs-container\>\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Biosketch\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Biosketch<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<p>Raffaella Bonecchi ha conseguito la laurea in Scienze Biologiche nel 1996 presso l\u2019Universit\u00e0 di Milano. Da allora ha lavorato nel contesto delle chemochine e recettori per chemochine, prima presso il Dipartimento di Immunologia e Biologia Cellulare presso l\u2019Istituto Mario Negri, dal 2000-2015 presso l\u2019Universit\u00e0 di Milano, come ricercatore e dal 2016 presso °µÍø½ûÇø University come professore associato.\n\nInizialmente si \u00e8 focalizzata sulla espressione differenziale dei recettori per chemochine da sottopopolazioni di linfociti T-helper e cellule dendritiche. Pi\u00f9 recentemente, la sua ricerca si \u00e8 concentrata sulla caratterizzazione del recettore atipico per chemochine ACKR2 e sul ruolo di questo recettore sulla biologia tumorale concentrandosi in particolare sul ruolo delle cellule dell\u2019immunit\u00e0 innata.<\/p>\n<\/div><\/div><\/div>\n\n\n\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Ricerca\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Ricerca<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<ul class=\wp-block-list\>\n<li>Immunit\u00e0 innata<\/li>\n\n\n\n<li>Infiammazione e cancro<\/li>\n\n\n\n<li>Monociti e macrofagi<\/li>\n\n\n\n<li>Chemochine e recettori<\/li>\n\n\n\n<li>Recettori atipici per chemochine<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\wp-block-hunimed-tabs-content-tab tabs-content-tab\><div class=\tab-item\ data-tab-title=\Pubblicazioni\><div class=\tab-header\><button class=\tab-nav\ role=\tab\ aria-selected=\false\><span class=\tab-title\>Pubblicazioni<\/span><\/button><\/div><div class=\tab-content\ role=\tabpanel\ aria-hidden=\true\>\n<ol class=\wp-block-list\>\n<li><strong>Bonecchi<\/strong>, R., G. Bianchi, P. P. Bordignon, D. D\u2019Ambrosio, R. Lang, A. Borsatti, S. Sozzani, P. Allavena, P. A. Gray, A. Mantovani, and F. Sinigaglia. <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/9419219\/\>Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s<\/a>.\u00a0<em>J Exp Med\u00a0<\/em>187:129-134.<\/li>\n\n\n\n<li>Mantovani, A.,\u00a0<strong>R. Bonecchi<\/strong>, and M. Locati. <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/17124512\/\>Tuning inflammation and immunity by chemokine sequestration: decoys and more<\/a>.\u00a0<em>Nat Rev Immunol\u00a0<\/em>6:907-918.<\/li>\n\n\n\n<li><strong>Bonecchi<\/strong>, R., E. M. Borroni, A. Anselmo, A. Doni, B. Savino, M. Mirolo, M. Fabbri, V. R. Jala, B. Haribabu, A. Mantovani, and M. Locati. <a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/18480427\/\>Regulation of D6 chemokine scavenging activity by ligand- and Rab11-dependent surface up-regulation<\/a>.\u00a0<em>Blood\u00a0<\/em>112:493-503.<\/li>\n\n\n\n<li>Savino, B., M. G. Castor, N. Caronni, A. Sarukhan, A. Anselmo, C. Buracchi, F. Benvenuti, V. Pinho, M. M. Teixeira, A. Mantovani, M. Locati, and\u00a0<strong>R. Bonecchi, <\/strong><a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/22504926\/\>Control of murine Ly6C(high) monocyte traffic and immunosuppressive activities by atypical chemokine receptor D6<\/a>. <em>Blood\u00a0<\/em>119:5250-5260<\/li>\n\n\n\n<li>Savino, B., N. Caronni, A. Anselmo, F. Pasqualini, E. M. Borroni, G. Basso, G. Celesti, L. Laghi, A. Tourlaki, V. Boneschi, L. Brambilla, M. Nebuloni, G. Vago, A. Mantovani, M. Locati, and R.\u00a0<strong>Bonecchi,<\/strong>\u00a0<a href=\https:\/\/pubmed.ncbi.nlm.nih.gov\/24844911\/\>ERK-dependent downregulation of the atypical chemokine receptor D6 drives tumor aggressiveness in Kaposi sarcoma<\/a>.\u00a0<em>Cancer Immunol Res\u00a0<\/em>2:679-689.<\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div>\n,protected:false},excerpt:{rendered:,protected:false},featured_media:49051,template:,departaments:[354],roles:[202,201],class_list:[post-11480,member,type-member,status-publish,has-post-thumbnail,hentry,departament-patologia-generale-3,role-associate-professor-it,role-professore-associato],acf:[],yoast_head:<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Raffaella Bonecchi - Hunimed<\/title>\n<meta name=\description\ content=\Biosketch Raffaella Bonecchi ha conseguito la laurea in Scienze Biologiche nel 1996 presso l\u2019Universit\u00e0 di Milano. 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